Research

Prism shares Astera Institute’s commitment to radical transparency. By publishing our work as it happens, we aim to maximize its potential for broad impact and reuse.

All of our research outputs are completely open, exist outside of traditional scientific journals, and aim to be FAIR: Findable, Accessible, Interoperable, and Reusable.

Research area

Code

- Modeling
06.22.26
macromolecular-observables
Opens on github.com/prism-science/macromolecular-observables
A package for conveying and transforming information about proteins — ensembles, structures, and measurements. A joint project of Radial Science and Reciprocal Spaceship.
- Code
- Modeling
05.24.26
consensus_water_analysis
Opens on github.com/prism-science/consensus_water_analysis
Analysis of consensus ordered water across Protein Data Bank depositions.
- Code
- Modeling
05.12.26
qFitLatent
Opens on github.com/prism-science/qFitLatent
A model to learn qFit multiconformer dynamics with an invariant backbone.
- Code
- Encoding
04.30.26
pdbx_hierarchy
Opens on github.com/prism-science/pdbx_hierarchy
Tools for working with hierarchical heterogeneity mmCIF models.
- Code
- Encoding
- and Modeling
04.28.26
mmcif_encoding
Opens on github.com/prism-science/mmcif_encoding
Examples and descriptions related to mmCIF encoding of hierarchical heterogeneity.
- Code
- Modeling
04.20.26
md-workflows
Opens on github.com/prism-science/md-workflows
Molecular dynamics workflows for simulating diffuse scattering.
- Code
- Diffuse Scattering
- and Modeling
04.13.26
goodvibes
Opens on github.com/prism-science/goodvibes
Lattice vibration model for diffuse scattering
- Code
- Diffuse Scattering
- and Data Collection
03.17.26
mdx2-workflows
Opens on github.com/prism-science/mdx2-workflows
Workflows for diffuse scattering data reduction with mdx2.
- Code
- Modeling
12.08.25
WaterFlow
Opens on github.com/prism-science/WaterFlow
Predicting water molecule placements on protein surfaces using flow matching conditioned on learned protein structure embeddings.
- Code
- Modeling
10.07.25
sampleworks
Opens on github.com/prism-science/sampleworks
Framework for modified sampling from biomolecular generative models
- Code
- Diffuse Scattering
- and Infrastructure and Data Collection
07.22.25
logbook
Opens on github.com/prism-science/logbook
Analysis notebooks for the diffUSE project.
- Code
- Dataset